Article
Role of flagellum and motility in pathogenesis of Vibrio vulnificus.
Infection and immunity - 1 Aug 2004
Lee Jong-Ho, Rho Jong Bok, Park Kyung-Je, Kim Chang Beom, Han Yang-Soo, Choi Sang Ho, Lee Kyu-Ho, Park Soon-Jung
Abstract excerpt
To assess the role of the flagellum which was detected by immunoscreening of surface proteins of Vibrio vulnificus, an flgE-deleted mutant was constructed and tested for its pathogenicity. The ability of this nonmotile mutant to adhere to INT-407 cells and its role in biofilm were decreased, as was its lethality to mice.
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