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Article

Flagellar basal body flg operon as a virulence determinant of Vibrio vulnificus.

Biochemical and biophysical research communications - 2 May 2003

Ran Kim Young, Haeng Rhee Joon

Abstract excerpt

Vibrio vulnificus, a halophilic estuarine bacterium causing a rapidly progressing fatal septicemia, is highly cytotoxic to eukaryotic cells. To identify new virulence factors associated with cytotoxicity, we constructed a mariner-based transposon (Tn Himar1) library of the highly virulent clinical isolate MO6-24/O having a double mutation in the hemolysin and protease genes. The Himar1 mutant library was...

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PMID: 12711330
DOI: 10.1016/s0006-291x(03)00613-2

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