Article
Oocyte-somatic cell interactions during follicle development in mammals.
Animal reproduction science - 1 Jul 2004
Gilchrist R B, Ritter L J, Armstrong D T
Abstract excerpt
Our current perspectives on the relationship between the oocyte and its surrounding somatic cells are changing as we gain a greater understanding of factors regulating folliculogenesis. It is now widely accepted that the oocyte plays a very active role in promoting follicle growth and directing granulosa cell differentiation. The oocyte achieves this, in part, by secreting soluble paracrine growth factors that...
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