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Article

Role of oocyte‐derived paracrine factors in follicular development

9 Apr 2014

Abstract excerpt

Mammalian oocytes secrete transforming growth factor β (TGF-β) superfamily proteins, such as growth differentiation factor 9 (GDF9), bone morphogenetic protein 6 (BMP6) and BMP15, and fibroblast growth factors (FGFs). These oocyte-derived paracrine factors (ODPFs) play essential roles in regulating the differentiation and function of somatic granulosa cells as well as the development of ovarian follicles. In...

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PMID: 24717179
DOI: 10.1111/asj.12200

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