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Follicular somatic cell factors and follicle development

7 Dec 2010

Abstract excerpt

Considerable attention is currently paid to oocyte-derived secreted factors that act upon cumulus and granulosa cells. Also important for follicle development are somatic cell-derived secreted factors. This is illustrated by the ability of granulosa cell-derived Kit ligand (KITL) to promote primordial follicle activation, and the loss of follicle development that accompanies KITL gene disruption. This review...

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PMID: 21366978
DOI: 10.1071/rd10224

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