Article
Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae.
The Journal of biological chemistry - 15 Sept 1992
Caplan A J, Tsai J, Casey P J, Douglas M G
Abstract excerpt
The Saccharomyces cerevisiae YDJ1 protein (YDJ1p) contains a C-terminal "CaaX box" motif common to proteins that are modified by prenylation. In the present study we show that YDJ1p is a specific substrate for both yeast and mammalian protein farnesyltransferase enzymes in vitro. A mutant form of...
Topics
- Alkyl and Aryl Transferases
- Electrophoresis, Polyacrylamide Gel
- Fungal Proteins
- HSP40 Heat-Shock Proteins
- Heat-Shock Proteins
- Hot Temperature
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Substrate Specificity
- Transferases
