Article
Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase.
The Journal of biological chemistry - 18 Jul 2008
Han Gil-Soo, O'Hara Laura, Siniossoglou Symeon, Carman George M
Abstract excerpt
The Saccharomyces cerevisiae DGK1 gene encodes a diacylglycerol kinase enzyme that catalyzes the formation of phosphatidate from diacylglycerol. Unlike the diacylglycerol kinases from bacteria, plants, and animals, the yeast enzyme utilizes CTP, instead of ATP, as the phosphate donor in the reaction. Dgk1p contains a CTP transferase domain that is present in the SEC59-encoded dolichol kinase and CDS1-encoded...
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