Article
Solution stability and variability in a simple model of globular proteins.
The Journal of chemical physics - 8 Jan 2004
Sear Richard P
Abstract excerpt
It is well known among molecular biologists that proteins with a common ancestor and that perform the same function in similar organisms, can have rather different amino-acid sequences. Mutations have altered the amino-acid sequences without affecting the function. A simple model of a protein in which the interactions are encoded by sequences of bits is introduced, and used to study how mutations can change these...
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