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Article

Increased Expression of Metallothionein Is Associated with Irinotecan Resistance in Gastric Cancer

15 Jul 2004

Abstract excerpt

To gain insight into clinically relevant mechanisms of irinotecan resistance, we undertook oligonucleotide microarray analyses on paired malignant effusion samples obtained from eight gastric cancer patients treated with weekly irinotecan. Pretreatment and posttreatment (48 h) effusion samples were obtained for each patient, and the change in expression profile was compared between clinical responders and...

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PMID: 15256434
DOI: 10.1158/0008-5472.can-04-1063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Increased Expression of Metallothionein Is Associated with Irinotecan Resistance in Gastric CancerPMID 15256434Read ↗

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