Article
Molecular evidence linking primary cancer of the fallopian tube to BRCA1 germline mutations.
Gynecologic oncology - 1 Jan 2000
Zweemer R P, van Diest P J, Verheijen R H, Ryan A, Gille J J, Sijmons R H, Jacobs I J, Menko F H, Kenemans P
Abstract excerpt
OBJECTIVES: BRCA1 and BRCA2 germline mutations increase the risk of ovarian and breast cancer. Fallopian tube cancer has occasionally been observed in breast-ovarian cancer families. At our family cancer clinic we recently encountered two cases of Fallopian tube cancer within two families harboring a BRCA1 germline mutation. To study the relationship between Fallopian tube cancer and BRCA1 mutations, a...
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