Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Degenerate in vitro genetic selection reveals mutations that diminish alfalfa mosaic virus RNA replication without affecting coat protein binding.

Journal of virology - 1 Aug 2004

Rocheleau Gail, Petrillo Jessica, Guogas Laura, Gehrke Lee

Abstract excerpt

The alfalfa mosaic virus (AMV) RNAs are infectious only in the presence of the viral coat protein; however, the mechanisms describing coat protein's role during replication are disputed. We reasoned that mechanistic details might be revealed by identifying RNA mutations in the 3'-terminal coat protein binding domain that increased or decreased RNA replication without affecting coat protein binding. Degenerate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Capsid Proteins

Share to Nucleic Acid Conformation

Share to Protein Binding

Share to Protein Biosynthesis

Share to RNA, Viral

Source

Open in PubMed Open full text

Identifiers

PMID: 15254175
DOI: 10.1128/JVI.78.15.8036-8046.2004
PMCID: PMC446135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Degenerate in vitro genetic selection reveals mutations that diminish alfalfa mosaic virus RNA replication without affecting coat protein binding.PMID 15254175Read ↗

Spatial determinants of the alfalfa mosaic virus coat protein binding site.Semantic proximity Read ↗

Genetic dissection of the multiple functions of alfalfa mosaic virus coat protein in viral RNA replication, encapsidation, and movement.Semantic proximity Read ↗

N-terminal basic amino acids of alfalfa mosaic virus coat protein involved in the initiation of infection.Semantic proximity Read ↗

Evidence for the role of basic amino acids in the coat protein arm region of Cucumber necrosis virus in particle assembly and selective encapsidation of viral RNA.Semantic proximity Read ↗

Deletion of repeated sequences from tobacco mosaic virus mutants with two coat protein genes.Semantic proximity Read ↗

Replication of Alfamo- and Ilarviruses: Role of the Coat ProteinSemantic proximity Read ↗

Comparison of the role of 5' terminal sequences of alfalfa mosaic virus RNAs 1, 2, and 3 in viral RNA replication.Semantic proximity Read ↗

Interaction of the cauliflower mosaic virus coat protein with the pregenomic RNA leader.Semantic proximity Read ↗

Evidence for a functional RNA element in the hepatitis C virus core gene.Semantic proximity Read ↗

Efficient translation of alfamovirus RNAs requires the binding of coat protein dimers to the 3' termini of the viral RNAs.Semantic proximity Read ↗

Mutational analysis of bean yellow dwarf virus, a geminivirus of the genus Mastrevirus that is adapted to dicotyledonous plants.Semantic proximity Read ↗

Functional analysis of dengue virus cyclization sequences located at the 5' and 3'UTRs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.