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Global expression analysis of two-component system regulator genes during Mycobacterium tuberculosis growth in human macrophages

17 Jun 2004

Abstract excerpt

In the Mycobacterium tuberculosis H37Rv genome, there are 11 paired two-component regulatory system genes, two orphan histidine kinase genes, and six orphan response regulator genes. Expression of the 17 response regulator genes and the two orphan histidine kinase genes during growth of M. tuberculosis in human peripheral blood monocyte-derived macrophages has been analyzed by using cDNA mixtures prepared by the...

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PMID: 15251217
DOI: 10.1016/j.femsle.2004.06.010

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