Article
Target SNP selection in complex disease association studies.
BMC bioinformatics - 12 Jul 2004
Wjst Matthias
Abstract excerpt
BACKGROUND: The massive amount of SNP data stored at public internet sites provides unprecedented access to human genetic variation. Selecting target SNP for disease-gene association studies is currently done more or less randomly as decision rules for the selection of functional relevant SNPs are not available. RESULTS: We implemented a computational pipeline that retrieves the genomic sequence of target genes,...
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