Article
Mammographic density in relation to daidzein-metabolizing phenotypes in overweight, postmenopausal women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2004
Frankenfeld Cara L, McTiernan Anne, Aiello Erin J, Thomas Wendy K, LaCroix Kristin, Schramm Judy, Schwartz Stephen M, Holt Victoria L, Lampe Johanna W
Abstract excerpt
Circulating hormones are associated with mammographic density, an intermediate marker of breast cancer risk. Differences in circulating hormones, including estrone and testosterone, have been observed in premenopausal women based on their capacity to metabolize daidzein, an isoflavone found predominantly in soybeans. Equol and O-desmethylangolensin (O-DMA) are products of intestinal bacterial metabolism of...
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