Article
Analytical study of the effect of recombination on evolution via DNA shuffling.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 May 2004
Peng Weiqun, Levine Herbert, Hwa Terence, Kessler David A
Abstract excerpt
DNA shuffling is an evolutionary protocol wherein cycles of selection, recombination, mutation, and amplification are employed to evolve proteins and DNA sequences. Experiments have shown its superiority to traditional protocols which do not employ recombination. Motivated by DNA shuffling, we investigate a multilocus evolutionary model that incorporates selection, recombination, and point mutations. Due to...
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