Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis C virus genotype 1a NS5A pretreatment sequence variation and viral kinetics in African American and white patients.

The Journal of infectious diseases - 15 Sept 2005

Layden-Almer Jennifer E, Kuiken Carla, Ribeiro Ruy M, Kunstman Kevin J, Perelson Alan S, Layden Thomas J, Wolinsky Steven M

Abstract excerpt

In hepatitis C virus (HCV) infection, race is a determinant of treatment response and interferon (IFN) effectiveness. Here, we investigated whether there were differences in the pretreatment viral strains between African American patients and white patients and whether these differences correlated with viral kinetics. IFN effectiveness was calculated using a viral kinetic model. The HCV NS5A region from 21...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Antiviral Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Hepacivirus

Share to Hepatitis C

Share to Interferons

Share to Viral Nonstructural Proteins

Share to White People

Source

Identifiers

PMID: 16107963
DOI: 10.1086/432760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis C virus genotype 1a NS5A pretreatment sequence variation and viral kinetics in African American and white patients.PMID 16107963Read ↗

Viral dynamics and response differences in HCV-infected African American and white patients treated with IFN and ribavirin.Semantic proximity Read ↗

Contribution of genome-wide HCV genetic differences to outcome of interferon-based therapy in Caucasian American and African American patients.Semantic proximity Read ↗

Treatment of chronic hepatitis C virus in African Americans with genotypes 2 and 3.Semantic proximity Read ↗

Hepatitis C virus infection in African Americans.Semantic proximity Read ↗

Early changes in hepatitis C virus (HCV) levels in response to peginterferon and ribavirin treatment in patients with chronic HCV genotype 1 infection.Semantic proximity Read ↗

Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1.Semantic proximity Read ↗

Complexity and diversity of hepatitis C virus RNA in african americans and whites: analysis of the envelope-coding domain.Semantic proximity Read ↗

Pretreatment sequence diversity differences in the full-length hepatitis C virus open reading frame correlate with early response to therapy.Semantic proximity Read ↗

Factors influencing treatment outcome in hepatitis C virus minority patients at an inner-city hospital: A STROBE-complaint article.Semantic proximity Read ↗

The impact of ethnicity on hepatitis C virus treatment decisions and outcomes.Semantic proximity Read ↗

Hepatitis C hypervariable region 1: association of reduced selection pressure in african americans with treatment failure.Semantic proximity Read ↗

Sustained virological response rate to pegylated interferon plus ribavirin for chronic hepatitis C in African Americans: results in treatment-naïve patients in a university liver clinic.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.