Article
Genomic imprinting of H19 in naturally reproduced and cloned cattle.
Biology of reproduction - 1 Nov 2004
Zhang Shouquan, Kubota Chikara, Yang Lan, Zhang Yuqin, Page Raymond, O'Neill Michael, Yang Xiangzhong, Tian X Cindy
Abstract excerpt
Animals produced from assisted reproductive technologies suffer from developmental abnormalities and early fetal death at a higher frequency than that observed in those produced by natural breeding. These symptoms are reminiscent of imprinting disruptions in the human and mouse, suggesting the possibility of perturbations in the expression of imprinted genes such as biallelic expression or silencing. H19 is one...
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