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Article

JAB1 participates in unfolded protein responses by association and dissociation with IRE1.

Neurochemistry international - 1 Oct 2004

Oono Kayoko, Yoneda Takunari, Manabe Takayuki, Yamagishi Satoru, Matsuda Satoshi, Hitomi Junichi, Miyata Shingo, Mizuno Tatsuyoshi, Imaizumi Kazunori, Katayama Taiichi, Tohyama Masaya

Abstract excerpt

Recent papers have reported that neuronal death in patients with Alzheimer's disease, Parkinson's disease, and cerebral ischemia has its origin in the endoplasmic reticulum (ER). IRE1alpha is one of the ER stress transducers that detect the accumulation of unfolded proteins in the ER. IRE1alpha mediates two major cellular responses, which are the unfolded protein response (UPR), a defensive response, and...

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PMID: 15234121
DOI: 10.1016/j.neuint.2004.01.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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