Article
Polymorphism of promotor region of the tumor necrosis factor-alpha gene in patients with viral hepatitis C.
Bulletin of experimental biology and medicine - 1 Mar 2004
Smol'nikova M V, Avdoshina V V, Tolokonskaya N P, Kolesnikov A P, Konenkov V I
Abstract excerpt
Study of the pathogenesis of viral hepatitis C is of primary importance because of persistence of this virus and high incidence of chronic course of this disease, and as a consequence, development of cirrhotic and neoplastic processes in the liver determining high mortality from this condition. Proinflammatory cytokines, in particular, tumor necrosis factor, play an important role in the development of these...
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