Article
Activation of tumor necrosis factor-alpha system in chronic hepatitis C virus infection.
Digestive diseases and sciences - 1 Dec 1997
Nelson D R, Lim H L, Marousis C G, Fang J W, Davis G L, Shen L, Urdea M S, Kolberg J A, Lau J Y
Abstract excerpt
Tumor necrosis factor-alpha (TNF-alpha) plays a central role in the host's immunomodulatory response to infective agents. To evaluate the TNF-alpha system in patients with chronic hepatitis C virus (HCV) infection, plasma, serum, and peripheral blood mononuclear cells (PBMC) were prospectively collected from 53 patients and 33 healthy control subjects. Circulating TNF-alpha and TNF receptors were assayed by their...
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