Article
Homozygosity of the T allele of the 46 C->T polymorphism in the F12 gene is a risk factor for ischemic stroke in the Spanish population.
Stroke - 1 Aug 2004
Santamaría Amparo, Mateo José, Tirado Isabel, Oliver Arturo, Belvís Roberto, Martí-Fábregas Joan, Felices Rosa, Soria José Manuel, Souto Juan Carlos, Fontcuberta Jordi
Abstract excerpt
BACKGROUND AND PURPOSE: Ischemic stroke (IS) is a complex disease that involves genetic and environmental factors. In a family-based study (the Genetic Analysis of Idiopathic Thrombophilia [GAIT] Project) that included a genome-wide scan, we demonstrated that a common polymorphism (46 C-->T) in t...
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