Article
Homozygosity for the C46T polymorphism of the F12 gene is a risk factor for venous thrombosis during the first pregnancy.
Journal of thrombosis and haemostasis : JTH - 1 Apr 2007
Cochery-Nouvellon E, Mercier E, Lissalde-Lavigne G, Daurès J-P, Quéré I, Dauzat M, Marès P, Gris J-C
Abstract excerpt
BACKGROUND: A first thromboembolic event during pregnancy and puerperium is predisposed to by polymorphisms G1691A in the factor V gene (F5) (F5G1691A) and G20210A in the prothrombin gene (F2) (F2G20210A). OBJECTIVES: To study another potentially frequent thrombogenic polymorphism, C46T in the factor XII gene (F12) (F12C46T). PATIENTS AND METHODS: The 32 463 previously asymptomatic women included in the NOHA...
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