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Helicobacter pyloriFlgR Is an Enhancer-Independent Activator of σ54-RNA Polymerase Holoenzyme

1 Jul 2004

Abstract excerpt

Helicobacter pylori FlgR activates transcription with sigma54-RNA polymerase holoenzyme (sigma54-holoenzyme) from at least five flagellar operons. Activators of sigma54-holoenzyme generally bind enhancer sequences located >70 bp upstream of the promoter and contact sigma54-holoenzyme bound at the promoter through DNA looping to activate transcription. H. pylori FlgR lacks the carboxy-terminal DNA-binding domain...

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PMID: 15231786
DOI: 10.1128/jb.186.14.4535-4542.2004

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