Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori.

doi:10.1111/j.1365-2958.2004.04006.x

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Article

Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori.

Molecular microbiology - 1 May 2004

Niehus Eike, Gressmann Helga, Ye Fang, Schlapbach Ralph, Dehio Michaela, Dehio Christoph, Stack Allison, Meyer Thomas F, Suerbaum Sebastian, Josenhans Christine

Abstract excerpt

The flagellar system of Helicobacter pylori, which comprises more than 40 mostly unclustered genes, is essential for colonization of the human stomach mucosa. In order to elucidate the complex transcriptional circuitry of flagellar biosynthesis in H. pylori and its link to other cell functions, mutants in regulatory genes governing flagellar biosynthesis (rpoN, flgR, flhA, flhF, HP0244) and whole-genome...

Topics

Bacterial Proteins
Base Sequence
Chemotaxis
DNA-Binding Proteins
DNA-Directed RNA Polymerases
Feedback, Physiological
Flagella
Gene Expression Profiling
Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Bacterial

Helicobacter pylori

Histidine Kinase

Membrane Proteins

Molecular Sequence Data

Monomeric GTP-Binding Proteins

Mutation

Oligonucleotide Array Sequence Analysis

Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 15130117
DOI: 10.1111/j.1365-2958.2004.04006.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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