Article
Analysis of the Campylobacter jejuni FlgR response regulator suggests integration of diverse mechanisms to activate an NtrC-like protein.
Journal of bacteriology - 1 Apr 2008
Joslin Stephanie N, Hendrixson David R
Abstract excerpt
Flagellar motility in Campylobacter jejuni mediates optimal interactions with human or animal hosts. Sigma(54) and the FlgSR two-component system are necessary for the expression of many C. jejuni flagellar genes. The FlgR response regulator is homologous to the NtrC family of transcriptional activators. These regulators usually contain an N-terminal receiver domain, a central domain that interacts with sigma(54)...
Topics
- Bacterial Proteins
- Campylobacter jejuni
- Electrophoretic Mobility Shift Assay
- Gene Expression Regulation, Bacterial
- Microscopy, Electron, Transmission
- Models, Genetic
- Phenotype
- Phosphorylation
- Protein Structure, Tertiary
- RNA Polymerase Sigma 54
- Trans-Activators