Article
Association of p53 arginine polymorphism with skin cancer.
International journal of dermatology - 1 Jul 2004
de Oliveira Walmar Roncalli P, Rady Peter L, Grady James, Hughes Thomas K, Neto Cyro F, Rivitti Evandro A, Tyring Stephen K
Abstract excerpt
BACKGROUND: The presence of arginine at codon 72 in p53 protein is proposed to be a genetic risk factor in human papillomavirus (HPV)-related carcinogenesis. OBJECTIVE: To study the prevalence of p53 polymorphism at codon 72 in skin biopsies of epidermodysplasia verruciformis (EV) patients compared to DNA samples from healthy individuals. PATIENTS AND METHODS: DNA samples extracted from normal skin and tumor...
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