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Article

Optimizing buccal cell DNA yields in mothers and infants for human leukocyte antigen genotyping.

American journal of epidemiology - 1 Jul 2004

Saftlas Audrey F, Waldschmidt Marianella, Logsden-Sackett Nyla, Triche Elizabeth, Field Elizabeth

Abstract excerpt

Buccal cells provide a convenient source of DNA for epidemiologic studies. Mouthwash rinses yield a higher quality and quantity of DNA than cytobrushes but are not practical for collection from infants. Although cytobrushes yield sufficient DNA for most genotyping analyses, human leukocyte antigen (HLA) analysis can require 1,000-fold more DNA. In Iowa City, Iowa, in 2002, the authors tested two cytobrush...

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PMID: 15229120
DOI: 10.1093/aje/kwh171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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