Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular architecture of CAG repeats in human disease related transcripts.

Journal of molecular biology - 16 Jul 2004

Michlewski Gracjan, Krzyzosiak Wlodzimierz J

Abstract excerpt

CAG repeats are present in numerous human transcripts but neither their structures nor physiological functions have been satisfactorily recognized. The expanded CAG repeats are present in transcripts from several mutant genes associated with hereditary neurodegenerative diseases but their contribution to pathogenesis has not been documented convincingly. Here, we show that the structures formed by the repeats and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxin-3
Share to Calcium Channels
Share to Huntington Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Myoclonic Epilepsies, Progressive

Share to Phosphorus Radioisotopes

Share to Spinocerebellar Ataxias

Share to Trinucleotide Repeat Expansion

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 15223312
DOI: 10.1016/j.jmb.2004.05.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular architecture of CAG repeats in human disease related transcripts.PMID 15223312Read ↗

Structures of trinucleotide repeats in human transcripts and their functional implications.Semantic proximity Read ↗

Imperfect CAG repeats form diverse structures in SCA1 transcripts.Semantic proximity Read ↗

RNA structure of trinucleotide repeats associated with human neurological diseases.Semantic proximity Read ↗

Genetic Variation in ATXN3 (Ataxin-3) 3'UTR: Insights into the Downstream Regulatory Elements of the Causative Gene of Machado-Joseph Disease/Spinocerebellar Ataxia Type 3.Semantic proximity Read ↗

A systematic analysis of disease-associated variants in the 3' regulatory regions of human protein-coding genes I: general principles and overview.Semantic proximity Read ↗

Comparative genetics of functional trinucleotide tandem repeats in humans and apes.Semantic proximity Read ↗

Structures of RNA repeats associated with neurological diseasesSemantic proximity Read ↗

Molecular cloning of a full-length cDNA for dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNS.Semantic proximity Read ↗

CCG•CGG interruptions in high penetrance SCA8 families increase RAN translation and protein toxicitySemantic proximity Read ↗

Overview of non-coding RNAs with CAG repeats and the case of mutation-containing circRNA in polyglutamine disease patientsSemantic proximity Read ↗

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseasesSemantic proximity Read ↗

Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loopsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.