Article
Association between schizophrenia and the syntaxin 1A gene.
Biological psychiatry - 1 Jul 2004
Wong Albert H C, Trakalo Joseph, Likhodi Olga, Yusuf Muneeb, Macedo Antonio, Azevedo Maria-Helena, Klempan Tim, Pato Michele T, Honer William G, Pato Carlos N, Van Tol Hubert H M, Kennedy James L
Abstract excerpt
BACKGROUND: Both microarray and candidate molecule studies have demonstrated that protein and mRNA expression of syntaxin and other genes involved in synaptic function are altered in the cerebral cortex of patients with schizophrenia. METHODS: Genetic association between polymorphic markers in the syntaxin 1A gene and schizophrenia was assessed in a matched case-control sample of 192 pairs, and in an independent...
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