Article
Evidence of syntaxin 1A involvement in migraine susceptibility: a Portuguese study.
Archives of neurology - 1 Apr 2010
Lemos Carolina, Pereira-Monteiro José, Mendonça Denisa, Ramos Eliana Marisa, Barros José, Sequeiros Jorge, Alonso Isabel, Sousa Alda
Abstract excerpt
OBJECTIVE: To confirm syntaxin 1A as a risk factor for migraine, given that syntaxin 1A interacts with several factors in migraine pathophysiology. DESIGN: Case-control approach. SETTING: An outpatient clinic. PARTICIPANTS: In a sample of 188 migraineurs (111 without aura and 77 with aura) and 287 migraine-free controls, 3 tagging SNPs of STX1A (rs3793243, rs941298, and rs6951030) were analyzed. A backward...
Read the complete abstract on PubMed