Article
Isolation and characterization of an analogue-resistant aminoacyl-tRNA synthetase mutant in Aspergillus nidulans.
Indian journal of experimental biology - 1 Feb 1992
Singh N K, Tiwary B N
Abstract excerpt
Six mutants resistant to p-fluorophenylalanine (FPA) were selected on a medium containing aspartate as the sole source of nitrogen using a phenylalanine-requiring (phenA)auxotroph of A. nidulans as the wild type. The mutants, on the basis of genetic characterization, were found to be alleilic and located on the left arm of the linkage group III, approximately 13 map unit left to meth H locus, henceforth assigned...
Topics
- Alleles
- Amino Acyl-tRNA Synthetases
- Aspergillus nidulans
- Chromosome Mapping
- Drug Resistance, Microbial
- Genes, Dominant
- Genetic Linkage
- Mutation
- p-Fluorophenylalanine
