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Article

In vitro and in vivo characterization of the minimal promoter region of the human thiamin transporter SLC19A2

1 Sept 2003

Abstract excerpt

The molecular mechanisms involved in the regulation of thiamin transport in mammalian cells are poorly understood. Previous studies established that a human thiamin transporter, SLC19A2, plays a role in thiamin uptake in human tissues. We cloned the 5' regulatory region of the SLC19A2 gene, identified the minimal promoter required for basal activity, and located multiple putative cis elements. To further...

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PMID: 12900388
DOI: 10.1152/ajpcell.00076.2003

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