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Article

Histochemical study of Dom mouse: A model for Waardenburg-Hirschsprung's phenotype.

Journal of pediatric surgery - 1 Jul 2004

Brizzolara Antonella, Torre Michele, Favre Anna, Pini Prato Alessio, Bocciardi Renata, Martucciello Giuseppe

Abstract excerpt

BACKGROUND/PURPOSE: The spontaneous mouse mutant Dominant megacolon (Dom) represents the model of the Waardenburg-Hirschsprung's disease, a syndromic pathology, characterized by the association of pigmentation defects (PD), deafness, and Hirschsprung's disease (HD). The defect in Dom mouse is cau...

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Source

Identifiers

PMID: 15213907
DOI: 10.1016/j.jpedsurg.2004.03.046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15213907-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Histochemical study of Dom mouse: A model for Waardenburg-Hirschsprung's phenotype.PMID 15213907Read ↗

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The importance of having your SOX on: role of SOX10 in the development of neural crest-derived melanocytes and glia.Semantic proximity Read ↗

Refining the Sox10Dom/+ mouse model: A new breeding strategy with relevance to Hirschsprung disease genetics.Semantic proximity Read ↗

Combinatorial multiomic analysis from a pedigree of Sox10 <sup>Dom</sup> Hirschsprung mice implicates Dach1 as a modifier of Enteric Nervous System developmentSemantic proximity Read ↗

Early Death of Neural Crest Cells is Responsible for Total Enteric Aganglionosis in <i>Sox10</i><sup><i>Dom</i></sup>/<i>Sox10</i><sup><i>Dom</i></sup> Mouse EmbryosSemantic proximity Read ↗

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Genome-wide linkage identifies novel modifier loci of aganglionosis in the Sox10Dom model of Hirschsprung disease.Semantic proximity Read ↗

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