Article
Transcriptional responses of intestinal epithelial cells to infection with Vibrio cholerae.
Infection and immunity - 1 Jul 2004
Stokes Neil R, Zhou Xin, Meltzer Stephen J, Kaper James B
Abstract excerpt
Vibrio cholerae is a noninvasive enteric bacterium that causes the severe diarrheal disease cholera. Candidate cholera vaccines have been engineered by deleting genes encoding known virulence factors in V. cholerae; however, many of these attenuated strains were still reactogenic in human volunteers. In this study, DNA arrays were utilized to monitor the transcriptional responses of human intestinal epithelial...
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