Article
Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jun 2004
Wilderman Paula J, Sowa Nathaniel A, FitzGerald David J, FitzGerald Peter C, Gottesman Susan, Ochsner Urs A, Vasil Michael L
Abstract excerpt
In many bacteria, iron homeostasis is controlled primarily by the ferric uptake regulator (Fur), a transcriptional repressor. However, some genes, including those involved in iron storage, are positively regulated by Fur. A Fur-repressed regulatory small RNA (sRNA), RyhB, has been identified in Escherichia coli, and it has been demonstrated that negative regulation of genes by this sRNA is responsible for the...
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