Article
Allelic imbalance on 12q22-23 in serum circulating DNA of melanoma patients predicts disease outcome.
Cancer research - 15 Jun 2004
Fujimoto Akihide, O'Day Steven J, Taback Bret, Elashoff David, Hoon Dave S B
Abstract excerpt
Allelic imbalance (AI) encompassing the apoptotic protease-activating factor 1 (APAF-1) locus (12q22-23) is found frequently in metastatic melanoma. Circulating DNA with AI on 12q22-23 in serum was evaluated as a surrogate marker to predict biochemotherapy (BC) treatment response in melanoma patients. Sera were collected from 49 American Joint Committee on Cancer stage IV melanoma patients treated with BC. Serum...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.