Article
Characterization of Tetrahymena histone H2B variants and posttranslational populations by electron capture dissociation (ECD) Fourier transform ion cyclotron mass spectrometry (FT-ICR MS).
Molecular & cellular proteomics : MCP - 1 Sept 2004
Medzihradszky K F, Zhang X, Chalkley R J, Guan S, McFarland M A, Chalmers M J, Marshall A G, Diaz R L, Allis C D, Burlingame A L
Abstract excerpt
This work describes the nature and sequence information content of the electron capture dissociation mass spectra for the intact Tetrahymena histone H2B. Two major variants of this protein were present bearing nominal modifications of both +42 and +84 Da. This work describes identification of the nature of these two modifications. For example, using gas-phase selection and isolation of the +42-Da modified...
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