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Article

Phylogenomics of unusual histone H2A Variants in Bdelloid rotifers.

PLoS genetics - 1 Mar 2009

Van Doninck Karine, Mandigo Morgan L, Hur Jae H, Wang Peter, Guglielmini Julien, Milinkovitch Michel C, Lane William S, Meselson Matthew

Abstract excerpt

Rotifers of Class Bdelloidea are remarkable in having evolved for millions of years, apparently without males and meiosis. In addition, they are unusually resistant to desiccation and ionizing radiation and are able to repair hundreds of radiation-induced DNA double-strand breaks per genome with little effect on viability or reproduction. Because specific histone H2A variants are involved in DSB repair and...

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PMID: 19266019
DOI: 10.1371/journal.pgen.1000401
PMCID: PMC2642717

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