Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA Interference Targeting VP1 Inhibits Foot-and-Mouth Disease Virus Replication in BHK-21 Cells and Suckling Mice

11 Jun 2004

Abstract excerpt

RNA interference (RNAi) is a powerful tool to silence gene expression posttranscriptionally. In this study, we evaluated the antiviral potential of small interfering RNA (siRNA) targeting VP1 of foot-and-mouth disease virus (FMDV), which is essential during the life cycle of the virus and plays a key role in virus attachment to susceptible cells. We investigated in vivo the inhibitory effect of VP1-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to RNA Interference and Gene Delivery
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15194766
DOI: 10.1128/jvi.78.13.6900-6907.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA Interference Targeting VP1 Inhibits Foot-and-Mouth Disease Virus Replication in BHK-21 Cells and Suckling MicePMID 15194766Read ↗

Inhibition of foot-and-mouth disease virus replication by small interfering RNASemantic proximity Read ↗

Recovery of Infectious Foot-and-Mouth Disease Virus from Suckling Mice after Direct Inoculation with In Vitro-Transcribed RNASemantic proximity Read ↗

Multiple microRNAs targeted to internal ribosome entry site against foot-and-mouth disease virus infection in vitro and in vivoSemantic proximity Read ↗

RNA interference against animal viruses: how morbilliviruses generate extended diversity to escape small interfering RNA control.Semantic proximity Read ↗

IRES-mediated translation of foot-and-mouth disease virus (FMDV) in cultured cells derived from FMDV-susceptible and -insusceptible animalsSemantic proximity Read ↗

Investigation of the role of syndecan-1 in the entry of foot-and-mouth disease virus into the cellSemantic proximity Read ↗

Full-Length Genomic RNA of Foot-and-Mouth Disease Virus is Infectious for Cattle by InjectionSemantic proximity Read ↗

The foot-and-mouth disease virus leader proteinase gene is not required for viral replicationSemantic proximity Read ↗

Characterization of an acid-resistant mutant of foot-and-mouth disease virus.Semantic proximity Read ↗

RNA interference targeting UL25 gene as a gene therapy approach against BHV-1 virusSemantic proximity Read ↗

Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells.Semantic proximity Read ↗

The fibroblast growth factor homolog of Bombyx mori nucleopolyhedrovirus enhances systemic virus propagation in B. mori larvae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.