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Article

Redifferentiation of human hepatoma cells induced by synthesized coumarin.

Cell biology international - 1 Jan 2004

Pan Jing, Zhang Qi, Zhao Chen-yang, Zheng Rong-liang

Abstract excerpt

The effects of synthesized 7-OH-4-CH(3)-coumarin on proliferation and differentiation of human hepatoma carcinoma cell line, SMMC-7721, were examined. Results showed that 7-OH-4-CH(3)-coumarin suppressed the proliferation of the SMMC-7721 cells in a dose-dependent manner, with an IC(50) value of 356 +/- 1.8 .M, while concentrations< or =200 mM could trigger differentiation. After treatment with this compound at...

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Identifiers

PMID: 15193276
DOI: 10.1016/j.cellbi.2004.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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