Article
Reversing effect of dimethyl-4,4'-dimethoxy-5,6,5', 6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate (DDB) on the phenotypes of human hepatocarcinoma cells line.
Cancer letters - 12 Nov 1996
Liu Z, Liu G, Zhang S
Abstract excerpt
When human Bel-7402 hepatocarcinoma cell line grew in a medium containing 10(-4) M dimethyl-4,4'-dimethoxy-5,6,5', 6'-dimethylenedioxybiphynyl-2,2'-dicarboxylate (DDB), the secretion of alpha-fetoprotein (AFP) was significantly lower than the control cells, whereas the albumin (ALB) secretion was...
Topics
- Biphenyl Compounds
- Carcinoma, Hepatocellular
- Cyclic AMP
- Dioxoles
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Humans
- Liver Neoplasms
- Neoplasm Proteins
- Phenotype
- Serum Albumin
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
- Tyrosine Transaminase
- alpha-Fetoproteins
- gamma-Glutamyltransferase