Article
A trial of three antiretroviral regimens in HIV-1-infected children.
The New England journal of medicine - 10 Jun 2004
Luzuriaga Katherine, McManus Margaret, Mofenson Lynne, Britto Paula, Graham Bobbie, Sullivan John L
Abstract excerpt
BACKGROUND: Depletion of CD4 T-cell counts or progression of human immunodeficiency virus (HIV) disease occurs rapidly in children, but few data address the efficacy of aggressive therapy for HIV-infected children. METHODS: We evaluated the safety, tolerability, and activity of three regimens of antiretroviral therapy in a multicenter, open-label, phase 1-2 trial. Children infected with HIV type 1 (HIV-1) were...
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