Article
High throughput SNP genotyping with two mini-sequencing assays.
Acta biochimica et biophysica Sinica - 1 Jun 2004
Luo Chunqing, Deng Libin, Zeng Changqing
Abstract excerpt
Two mini-sequencing methods, FP-TDI (template-directed dye-terminator incorporation with fluorescence-polarization) and MassArray (matrix assisted laser desorption ionization time of flight detection mass spectrometry), were optimized. A numeric standard was introduced to evaluate the SNP scoring quality of FP-TDI assay, thus made the optimization work easier. At the same time, using multi-PCR technology, 8-plex...
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