Article
[Report of a case of congenital plasminogen activator inhibitor-1 deficiency].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2004
Zhang Zi-Yan, Wang Zhao-Yue, Fu Jian-Xin, Dong Ning-Zheng, Zhang Wei, Bai Xia, Ruan Chang-Geng
Abstract excerpt
OBJECTIVE: To report a patient with congenital plasminogen activator inhibitor-1 (PAI-1) deficiency and explore its molecular mechanism. METHODS: The activities of tissue plasminogen activator (tPA), alpha(2) antiplasmin (alpha(2)AP) and PAI-1 were measured by the methods of chromogenic substrate, the antigens of tPA and PAI-1 were measured by ELISA. PAI-1 gene was studied by PCR product sequencing and...
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