Article
[Genotype and phenotype analysis of congenital coagulator factor VII deficiency in four Chinese pedigrees].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2011
Jiang Ming-hua, Wang Zhao-yue, Yu Zi-qiang, Bai Xia, Cao Li-juan, Su Jian, Sun Xiong-hua, Zhang Wei, Ruan Chang-geng
Abstract excerpt
OBJECTIVE: To investigate the clinical manifestation and gene mutation in four Chinese pedigrees with the congenital coagulation factor VII deficiency. METHODS: Prothrombin time (PT), activated partial thromboplastin time, thrombin time and plasma fibrinogen were measured using STAGO STA-R automatic coagulation analyzer, and the coagulation activity of factor VII (FVII:C) was determined by a PT-based one stage...
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