Article
Genetic variations of apolipoprotein A5 gene is associated with the risk of coronary artery disease among Chinese in Taiwan.
Atherosclerosis - 1 Mar 2006
Hsu Lung-An, Ko Yu-Lin, Chang Chi-Jen, Hu Chiao-Feng, Wu Semon, Teng Ming-Sheng, Wang Chun-Li, Ho Wan-Jing, Ko Yu-Shien, Hsu Tsu-Shiu, Lee Ying-Shiung
Abstract excerpt
Recently, a T/C polymorphism of the promoter region of the APOA5 gene at position -1131 and a G/T polymorphism at position 553 were found to be associated with increased levels of plasma triglyceride. Triglyceride plays a role in coronary artery disease (CAD), so this case-control study tested for a possible link between these two APOA5 polymorphisms, their common haplotypes and the risk of CAD. The subjects...
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