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Article

Extensive genomic diversity in pathogenic Escherichia coli and Shigella Strains revealed by comparative genomic hybridization microarray.

Journal of bacteriology - 1 Jun 2004

Fukiya Satoru, Mizoguchi Hiroshi, Tobe Toru, Mori Hideo

Abstract excerpt

Escherichia coli, including the closely related genus Shigella, is a highly diverse species in terms of genome structure. Comparative genomic hybridization (CGH) microarray analysis was used to compare the gene content of E. coli K-12 with the gene contents of pathogenic strains. Missing genes in a pathogen were detected on a microarray slide spotted with 4,071 open reading frames (ORFs) of W3110, a commonly used...

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Identifiers

PMID: 15175305
DOI: 10.1128/JB.186.12.3911-3921.2004
PMCID: PMC419953

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