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Article

Frizzled6 controls hair patterning in mice

28 May 2004

Abstract excerpt

Hair whorls and other macroscopic hair patterns are found in a variety of mammalian species, including humans. We show here that Frizzled6 (Fz6), one member of a large family of integral membrane Wnt receptors, controls macroscopic hair patterning in the mouse. Fz6 is expressed in the skin and hair follicles, and targeted deletion of the Fz6 gene produces stereotyped whorls on the hind feet, variable whorls and...

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PMID: 15169958
DOI: 10.1073/pnas.0402802101

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