Article
In vitro exposure to macrolide antibiotics in Helicobacter pylori strains isolated from children.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Apr 2004
Fujimura Shigeru, Kato Seiichi, Iinuma Kazuie, Watanabe Akira
Abstract excerpt
Clarithromycin resistance of Helicobacter pylori is a serious problem in eradication therapy. We investigated whether the use of maclorides (clarithromycin, erythromycin, and azithromycin) induces clarithromycin resistance in the organism. Twenty H. pylori strains were isolated from pediatric patients with gastrointestinal symptoms. The minimum inhibitory concentrations (MICs) of each macrolide antibiotic were...
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