Article
The sequence of pbp2b from penicillin-resistant Streptococcus pneumoniae in Thailand.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Nov 2010
Tribuddharat Chanwit, Polwichai Pitimon, Champreeda Preecha, Srifuengfung Somporn
Abstract excerpt
OBJECTIVE: Penicillin resistance in Streptococcus pneumoniae isolates results from altered penicillin-binding proteins (PBPs), especially PBP2, which has a reduced affinity to penicillin. This study evaluated drug resistance and the gene sequence of the conserved motif pbp2b of penicillin-resistant isolates in Thailand. MATERIAL AND METHOD: Penicillin-resistant pneumococci with minimum inhibitory concentrations...
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